Actimask^® Ibuprofen

Actimask^{^®}taste-masked ibuprofen is an ideal choice for the formulation of chewable or orally dispersible dosage forms. The aqueous hydrophilic coating delivers an excellent taste barrier. In addition, the uniform hydrogel coating provides a smooth surface that has an excellent mouth feel and is easy to swallow.

Adding Value to Pharmaceutical Products

Actimask Ibuprofen exhibits minimal drug release in the oral cavity during the first few minutes of exposure thus avoiding the unpleasant taste and sensation associated with this active when swallowed. However, at gastric pH it exceeds USP/EP compendial dissolution requirements. An in vivo pharmacokinetic study has showed that formulations with Actimask Ibuprofen are comparable to other marketed products.

Actimask Ibuprofen is easy to use. It has good flow and is directly compressible making it perfect for direct compression applications. The high assay content allows for formulation flexibility and also helps to reduce the tablet weight of high dose formulations.

Actimask Ibuprofen Features & Benefits

Features	Benefits
Uniform Hydrogel Coating	Effective taste-mask prevents ibuprofen burning sensation Smooth organoleptics in orodispersibles No residual solvent
Rapid Drug Release	in vivo pharmacokinetics comparable to marketed products ODT meets compendial dissolution
High Assay	Provides formulating flexibility
Good Physical Characteristics	Easy to manufacture dose forms
Reputable Supplier	High quality and reliable supply
Bioavailable	Likely to be bioequivalent to marketed products